Hydroquinine, an organic compound found in the bark of some trees, and a drug used to treat malaria, is known to have bacterial killing activity which may help contact lens wearers.
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A new study suggests a naturally-occurring material is an effective disinfectant for contact lenses, worn by millions of people worldwide. Microbial keratitis is one of the most serious potential complications for contact lens wearers. It’s an infection of the cornea that is caused by bacteria; the most common being Pseudomonas aeruginosa.
Previous studies have found that existing disinfecting solutions are not effective for preventing biofilm, which are clusters of bacteria that attach to the surface of lenses.
Hydroquinine, an organic compound found in the bark of some trees, is known to have bacterial killing activity against Pseudomonas aeruginosa and several other clinically important germs, including Staphylococcus aureus, Escherichia coli, and Klebsiella pneumoniae.
The team behind the discovery, from the University of Portsmouth in England and Naresuan and Pibulsongkram Rajabhat universities in Thailand, has now explored the potential use of multipurpose formulas containing hydroquinine as a disinfectant for contact lenses.
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